TRIALS

1. Oxford Haemodynamic Adaptation to Reduce Pulsatility (OxHARP) trial
2. Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function trial (TREAT@SVDs)
3. Oxford Vascular Study (OxVASC)
4. Arterial Pulsatility in Small Vessel Diseases – Measurement of Arterial Pulsatility on MRI (OxBP)

PUBLISHED PAPERS

1. Kopczak A, S Stringer M, van den Brink H, Kerkhofs D, Blair GW, van Dinther M, Onkenhout L, Wartolowska KA, Thrippleton MJ, Duering M, Staals J, Middeke M, André E, Norrving B, Bousser M-G, Mansmann U, Rothwell PM, Doubal FN, van Oostenbrugge R, Biessels GJ, Webb AJS, Wardlaw JM, Dichgans M, on behalf of the SVDs@target consortium. The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial. European Stroke Journal 2022;8:387-397.
2. Webb AJS, Wartolowska KA, Li L, Mazzucco S, Rothwell PM. Consistencies and differences in intermediate physiological phenotypes of vascular ageing between ischaemic stroke aetiologies. Cerebrovascular Diseases 2023;52(2):194-201.
3. Webb AJS, Wartolowska KA, Li L, Rothwell PM. Low heart rate is associated with cerebral pulsatility after TIA or minor stroke. Annals of Neurology 2022;92:909-920.
4. Wartolowska KA, Webb AJS. White matter damage due to pulsatile versus steady blood pressure differs by vascular territory: a cross-sectional analysis of the UK Biobank cohort study. Journal of Cerebral Blood Flow and Metabolism 2021;6:283-290.
5. Webb AJS, Lawson A, Wartolowska KA, Mazzucco S, Rothwell PM. Aortic stiffness, pulse pressure and cerebral pulsatility progress despite best medical management: the OxVASC cohort. Stroke 2022;53:1310–1317.
6. Wartolowska KA, Webb AJS. Big cohort studies offer insights into preventable risk factors. European Heart Journal 2021;42:4280–4281.
7. Webb AJS, Werring D, Dawson J, Rothman A, Lawson A, Wartolowska K. Design of a randomised, double-blind, crossover, placebo-controlled trial of effects of sildenafil on cerebrovascular function in small vessel disease: Oxford Haemodynamic Adaptation to Reduce Pulsatility Trial (OxHARP). European Stroke Journal 2021;6:283–290
8. Wartolowska KA, Webb AJS. Blood pressure determinants of cerebral white matter hyperintensities and microstructural injury: UK Biobank cohort study. Hypertension 2021;78:532-539.
9. Webb AJS, Lawson A, Wartolowska KA, Mazzucco S, Peter M Rothwell PM. Progression of Beat-to-Beat Blood Pressure Variability Despite Best Medical Management. Hypertension 2021;77:193-201
10. Wartolowska KA, Webb AJS. Midlife blood pressure is associated with the severity of white matter hyperintensities: analysis of the UK Biobank cohort study. European Heart Journal 2021; 42(7): 750–757.
11. Karaszewski B, Wardlaw JM, Marshall I, Cvoro V, Wartolowska K, Haga K, Armitage PA, Bastin ME, Dennis MS. Early brain temperature elevation and anaerobic metabolism in human acute ischaemic stroke. Brain 2009;32:955-964
12. Cvoro V, Wardlaw JM, Marshall I, Armitage PA, Rivers CS, Bastin ME, Carpenter TK, Wartolowska K, Farrall AJ, Dennis MS. Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke. Stroke 2009;40:767-772
13. Karaszewski B, Wardlaw JM, Marshall I, Cvoro V, Wartolowska K, Haga K, Armitage PA, Bastin ME, Dennis MS. Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke. Annals of Neurology 2006;60:438-446
14. Marshall I, Karaszewski B, Wardlaw JM, Cvoro V, Wartolowska K, Armitage PA, Carpenter T, Bastin ME, Farrall A, Haga K. Measurement of regional brain temperature using proton spectroscopic imaging: validation and application to acute ischemic stroke. Magnetic Resonance Imaging 2006;24:699-706
15. Wardlaw JM, Chappell FM, Best JJ, Wartolowska K, Berry E. NHS Research and Development Health Technology Assessment Carotid Stenosis Imaging Group. Non-invasive imaging compared with intra-arterial angiography in the diagnosis of symptomatic carotid stenosis: a meta-analysis. Lancet 2006;367:1503-1512
16. Marshall I, Papathanasopoulou P, Wartolowska K. Carotid flow rates and flow division at the bifurcation in healthy volunteers. Physiological Measurement 2004;25:691-697

CONFERENCE PRESENTATIONS

1. Wartolowska K and Webb AJS. Regional diffusion imaging changes related to obesity, after adjusting for other risk factors: the UK Biobank study. The 31th ISMRM Conference. London, UK.
2. Wartolowska K and Webb AJS. Complex interactions between obesity and white matter: UK Biobank study. European Stroke Organisation Conference. Virtual due to COVID.
3. Wartolowska K and Webb AJS. Effect of past and concurrent blood pressure above 120/70 on white matter hyperintensities: an analysis of the UK Biobank cohort. European Stroke Organisation-World Stroke Organisation Conference. Virtual due to COVID.
4. Wartolowska K and Webb AJS. Differential associations between macroscopic and microstructural white matter injury with constant and pulsatile blood pressure components: an analysis of the UK Biobank cohort. European Stroke Organisation-World Stroke Organisation Virtual Conference. Virtual due to COVID.
5. Croal PL, Ray KJ, Wartolowska K, Lawson A, Webb A, Jezzard P. Physiological correlates of brain pulsatility in cerebrovascular small vessel disease: a data-driven approach with high temporal resolution fMRI. ISMRM & SMRT Virtual Conference & Exhibition
6. Wartolowska K and Webb AJS. Mid-life diastolic blood pressure predicts excess future white matter hyperintensities more than systolic blood pressure: an analysis of the UK Biobank cohort. The Brain Prize Meeting: “Silently Loosing the Brain”. The Lundbeck Foundation. Copenhagen, Denmark
7. Cvoro V, Wardlaw JM, Wartolowska K , Farrall AJ, Marshall I, Armitage PA, Rivers CS, Bastin ME, Carpenter TK, Dennis MS. Lactate values in the acute stroke diffusion lesion vary with perfusion levels The 15th European Stroke Conference Brussels, Belgium (2006)
8. Wardlaw JM, Karaszewski BC, Marshall I, Cvoro V, Wartolowska K , Haga K, Armitage PA, Bastin ME. Dennis MS. Measurement of brain temperature with MR spectroscopy in patients with acute ischaemic stroke - temperature is highest in "penumbral" tissue British Society of Neuroradiologists Annual Scientific Meeting Edinburgh, UK. (2005)
9. Marshall I, Karaszewski B, Wardlaw JM, Cvoro V, Wartolowska K , Armitage PA, Carpenter T, Bastin M, Farrall A, Haga K, Dennis M. Measurement of regional brain temperature using proton spectroscopic imaging: preliminary results in acute ischaemic stroke European Society for Magnetic Resonance in Medicine and Biology (ESMRMB) Conference, Basel Switzerland (2005)